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 Introduction |
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The quality manager is responsible for all the standardisation and quality issues in the laboratory. DRIFTCON enables the quality manager to design the regulatory requirements for the thermal cyclers and the applications used. Typically, the quality manager has access to DRIFTCON at the administrator level. DRIFTCON allows the quality manager full access to the user management system, overall system settings and device management. Besides that the quality manager has full access to the trace ability and report options in the software.
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| Threshold settings |
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Threshold settings are used to compare the temperature performance of the cycler against (pre)-defined values. The quality manager has the possibility to set these thresholds into detail. These settings may then be used to determine if, or if not, the tested instrument is within specifications. The quality manager also decides on the test frequency of the PCR equipment, and makes clear definitions whether the threshold preferences are based on application(s) or on instruments.
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| Application-based thresholds |
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Although the design of the application thresholds is much more difficult and time-consuming, application thresholds are superior to instrument thresholds. In other words: application thresholds offer a real view whether or not the used cycler is suitable for this application. In case of a commercial (diagnostic) kit (PCR, LCR, Real-Time PCR, RT-PCR etc) one may request the temperature profile thresholds from the kit manufacturer. Should the kit manufacturer not have these thresholds available, then it’s worth considering visiting or participating in our discussion forum at the DRIFTCON website: www.driftcon.com
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| Instrument-based thresholds |
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Instruments thresholds (the average market performance for one specific instrument and block type) are provided with the purchase of a DRIFTCON system. Other brand/block-type specific threshold settings may be purchased as software “add-on” (optional). These specific instrument thresholds are extracted from the global database, which contains numerous measurements of machines of that same brand and type. These values are provided as a mean plus or minus 2x the standard deviation (so they equal 95% of the population).
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